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MILabs
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SCANCO USA INC
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SCANCO USA INC
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SCANCO USA INC
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Siemens AG
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MOLECUBES NV
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Image Search Results
Journal: Biomaterials Research
Article Title: The Strontium Ion Reprograms Monocyte Subsets via TRPM2 Channel Regulation to Enhance Osseointegration
doi: 10.34133/bmr.0286
Figure Lengend Snippet: Sr-SLA implants promoted bone formation. (A) Representative scanning electron microscopy (SEM) images of SLA and Sr-SLA surfaces (scale bars = 5 μm, 1 μm, and 250 nm). (B) Energy-dispersive x-ray spectrometry (EDS) spectra of SLA and Sr-SLA surfaces. (C) X-ray photoelectron spectroscopy (XPS) patterns of SLA and Sr-SLA surfaces. (D) Micro-computed tomography (micro-CT) evaluation of bone regeneration in the SLA and Sr-SLA groups at 3, 7, and 14 d after implantation (the pink area indicates new bone formation). n = 6 mice per group and per time point. (E) Bone volume fraction (BV/TV) and trabecular thickness (Tb.Th) of regenerated tissues surrounding implants at 3, 7, and 14 d after implantation in each group. (F) Hematoxylin and eosin (H&E) staining of paraffin sections in the SLA and Sr-SLA groups at 3, 7, and 14 d after implantation (scale bar = 500 μm at low magnification, scale bar = 200 μm at high magnification). n = 5 mice per group and per time point. (G) New bone area of regenerated tissues surrounding implants at 3, 7, and 14 d after implantation in each group. * P < 0.05; ** P < 0.01; **** P < 0.0001.
Article Snippet: Mouse tibia containing implants were collected and fixed with 4% paraformaldehyde (PFA; Beyotime, P0099) for 48 h. Analysis was performed using a
Techniques: Electron Microscopy, Spectroscopy, Micro-CT, Staining
Journal: Biomaterials Research
Article Title: The Strontium Ion Reprograms Monocyte Subsets via TRPM2 Channel Regulation to Enhance Osseointegration
doi: 10.34133/bmr.0286
Figure Lengend Snippet: Monocyte depletion impaired new bone formation. (A) Workflow of the experiments on monocyte depletion. (B) Flow cytometry analysis of cells stained by CD11b and Ly6G in the control and clodronate liposome (CLL) groups. n = 6 mice per group. (C) Statistical analysis of CD11b + Ly6G − cells in the control and CLL groups. (D) Micro-CT evaluation of bone regeneration in control and CLL groups at 7 and 14 d after implantation (the purple area indicates new bone formation). n = 6 mice per group and per time point. (E) BV/TV and Tb.Th of regenerated tissues surrounding implants 7 and 14 d after implantation in each group. (F) H&E staining of paraffin sections in the control and CLL groups 7 and 14 d after implantation (scale bar = 500 μm at low magnification, scale bar = 200 μm at high magnification). n = 5 mice per group and per time point. (G) New bone area of regenerated tissues surrounding implants 7 and 14 d after implantation in each group. ** P < 0.01; *** P < 0.001; **** P < 0.0001. FCM, flow cytometry.
Article Snippet: Mouse tibia containing implants were collected and fixed with 4% paraformaldehyde (PFA; Beyotime, P0099) for 48 h. Analysis was performed using a
Techniques: Flow Cytometry, Staining, Control, Micro-CT
Journal:
Article Title: Osseointegration into a Novel Titanium Foam Implant in the Distal Femur of a Rabbit
doi: 10.1002/jbm.b.31541
Figure Lengend Snippet: MicroCT images used to determine mode of failure after push-out testing. Crushing of the metal implant proximally occurred during push-out testing in a small pore titanium foam implant at 6 weeks (A). During push-out testing, a sintered beaded implant failed proximally within the bone (B) and a small pore titanium foam implant failed distally within the bone; both had been in vivo for 6 weeks. A large pore titanium foam implant in vivo for 12 weeks, failed at the bone-implant interface (D) during push-out testing.
Article Snippet: MicroCT Failure Analysis After push-out testing, a subset of 27 femurs (n=3/implant/time point) were imaged in a
Techniques: In Vivo